The codeine in acetaminophen and codeine phosphate tablets may possibly enhance the frequency of seizures in individuals with seizure Ailments, and should enhance the threat of seizures transpiring in other clinical options affiliated with seizures.

Opioid antagonists, which include naloxone, are specific antidotes to respiratory despair resulting from opioid overdose. For clinically important respiratory or circulatory despair secondary to acetaminophen and codeine overdose, administer an opioid antagonist.

Inform people that anaphylaxis has been claimed with ingredients contained in acetaminophen and codeine phosphate tablets. Recommend sufferers how to recognize this kind of response, and whenever they acquire signs of allergy like a rash or trouble breathing to stop getting acetaminophen and codeine phosphate tablets and find health care consideration (see CONTRAINDICATIONS and ADVERSE REACTIONS).

Ahead of taking acetaminophen and codeine phosphate tablets, notify your healthcare supplier if you have a record of: head injuries, seizures liver, kidney, thyroid challenges challenges urinating pancreas or gallbladder difficulties abuse of street or prescription drugs, Alcoholic beverages habit, opioid overdose, or mental health problems Have already been explained to by your Health care supplier that you'll be a “swift metabolizer” of particular medicines.

The minimum amount successful analgesic concentration of codeine for virtually any personal patient may possibly boost after a while due to an increase in soreness, the event of a completely new ache syndrome, and/or the event of analgesic tolerance (see DOSAGE AND ADMINISTRATION).

Just after halting usage of a CYP2D6 inhibitor, think about lowering the acetaminophen and codeine phosphate tablets and Appraise the patient for indications and indications of respiratory depression or sedation.

Retailer at place temperature away from dampness and warmth. Keep track of your medicine. Codeine can be a drug of abuse and try to be aware if any person is utilizing your medication improperly or without having a prescription.

Revatio® is employed to take care of a exceptional ailment known as pulmonary arterial hypertension (PAH). Cialis® and generic Cialis® really should not be employed with Revatio® or with click here other PAH solutions made up of sildenafil or every other PDE5 inhibitors (like Adcirca [tadalafil])

Tend not to continue to keep leftover opioid medication. Just one dose could potentially cause Loss of life in anyone employing this medicine unintentionally or improperly.

Clients who will be extremely-immediate metabolizers of codeine because of a website CYP450 2D6 polymorphism, will transform codeine additional fast and wholly read more to morphine resulting in unexpectedly high morphine levels, which may get more info be daily life-threatening.

Monitor clients for threat of substance use Conditions, which click here includes opioid abuse and misuse, and warn them of the danger for overdose and Loss of life associated with using added CNS depressants which includes alcohol and illicit medicine (see Safeguards, Drug Interactions and Details for Patients/Caregivers).

Get your prescribed dose each and every 4 several hours as wanted. Tend not to acquire in excess of your prescribed dose. In case you overlook a dose, get your up coming dose when wanted. Phone your healthcare supplier In the event the dose you're using will not Handle your discomfort.

So as to avoid producing withdrawal symptoms, instruct individuals to not discontinue acetaminophen and codeine phosphate tablets devoid of to start with discussing a tapering program Along with the prescriber (see DOSAGE AND ADMINISTRATION).

Get professional medical assist straight away In case you have any quite really serious Unintended effects, like: fainting, seizure.